hrp0089p3-p143 | Fat, Metabolism and Obesity P3 | ESPE2018

Acanthosis Nigricans in Obese Children and Adolescents in relation to Severity of Obesity and Insulin Resistance

Hee Park Kyung , Jung Lim Hyun , Myoung Kim Yoon

Acnathosis nigricans (AN) is known to be common dermatologic manifestation in obese children and adolescents. The aim of this study is to examine the association of AN and insulin resistance in obese children and adolescents. One hundred seventy-nine obese subjects aged 6-17 years who participated in the intervention study, Childhood and Adolescents Obesity via Activity and Nutrition (ICAAN) study, were enrolled in 2017-2017. AN was diagnosed by physician. Anthropomet...

hrp0092p1-429 | Thyroid (2) | ESPE2019

Genetic Evaluation of Congenital Hypothyroidism with Gland-In-Situ Using Targeted Exome Sequencing

Hyun Shin Jung , Young Kim Hye , Mi Kim Young , Lee Heirim , Hye Bae Mi , Hee Park Kyung , Lee Sae-Mi , Jung Kwak Min

Objective: To analyze the genetic cause of congenital hypothyroidism by targeted exome sequencing in pediatric patients with congenital hypothyroidism with thyroid gland in situ.Patient and Method: The study population comprised 20 patients with thyroid gland, who were diagnosed with congenital hypothyroidism at Pediatric Endocrinologic Clinic of Pusan National University Hospital. Targeted exome sequencing was ...